Episode 53: NMN and Longevity Part 1: The Science Behind Nicotinamide Mononucleotide

 

In this episode, we explore Nicotinamide Mononucleotide (NMN), a molecule that's generating buzz in the world of longevity science. We’ll delve into the science behind NMN, how it works in the body, and why it might be a key player in future anti-aging therapies. From cellular aging to enhancing both lifespan and healthspan, we’ll uncover the potential of NMN in supporting everything from reproduction to DNA repair, cognitive function, and metabolic health.

Starting with why this topic is crucial in our quest for longevity, we’ll discuss how NMN functions as a direct precursor to NAD+, a molecule vital for cellular repair and reducing inflammation. We’ll also explore how NMN supports mitochondrial function, protects against oxidative stress, and aids in DNA repair. Additionally, we’ll cover the latest research on NMN's impact on metabolic health, cognitive function, and cardiovascular health, along with its role in delaying or reversing cellular senescence, a key driver of aging and age-related diseases.

Whether you're new to this concept or looking to deepen your knowledge, this episode offers valuable insights into the ever-evolving world of longevity science. Don’t miss this deep dive into how NMN might be a game-changer for your health and vitality.

DISCLAIMER: The content in this podcast and related website is not intended to be a substitute for medical advice. It is not intended to be used to diagnose or treat, instead it is designed to help educate and inspire. Always seek the advice of a professional medical practitioner or qualified health practitioner. Never ignore or disregard advice given to you based on information in this podcast or related website and do not delay in seeking medical advice.

 

Timestamps:

[01:30] - Why this is so important, the quest for longevity and maximizing the years of wellness that we got

[03:55] - What exactly is NMN, how it functions within the body why is generating so much interested

[06:20] - Other cellular processes (regulating circadian rhythms, enhancing mitochondrial function)

[07:20] - The science behind NMN and longevity

[11:15] - NMN and metabolic health, cognitive function, cardiovascular health, and brain health

[14:36] - Cellular Senescence and NMN

[15:22] - Metabolic health and NMN

 
Given its impact on insulin sensitivity, inflammation, mitochondrial function, and longevity, NMN holds a significant potential for helping to prevent age-related metabolical diseases as well as benefiting us from the standpoint of longevity.
— Nicole Goode
 

Essential learnings from this episode…

  • The importance of NMN as a key player in future anti-aging therapies

  • NMN has the power to enhance both lifespan and healthspan

  • NMN functions as a direct precursor to NAD+

  • NMN is involved in cellular repair processes, regulates circadian rhythms, enhances mitochondrial function, and delays or reverses cellular senescence, among other functions

  • Key studies on NMN have been conducted on mice, and new clinical studies are on the way

 
 

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Episode 54: NMN and Longevity Part 2: The Action Steps for Optimal Health

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Episode 52: Diet, Hormones, and the Thyroid Connection with Dr. Dana Gibbs